Symptomatic hyponatraemia associated with tolbutamide therapy.
نویسنده
چکیده
A case of hyponatraemic coma occurring in a patient with diabetes mellitus treated with tolbutamide is described. Although chlorpropamide is known to cause water retention in some circumstances, this is a less well recognized complication of tolbutamide therapy.
منابع مشابه
Drug-induced hyponatraemia in psychogenic polydipsia.
Two patients with psychogenic polydipsia developed hyponatraemia, one in association with administration of hydrochlorothiazide and the other with that of tolbutamide. It is suggested that the increased fluid intake in such patients may make them more susceptible to the development of hyponatraemia from thiazide or sulphonylurea compounds.
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عنوان ژورنال:
- Postgraduate medical journal
دوره 53 618 شماره
صفحات -
تاریخ انتشار 1977